The natural habits of chameleons make them tricky to care for - they are arboreal, living exclusively in trees. They are solitary, and easily stressed. As a result, they need a cage with ample foliage for climbing and privacy. The enclosure must be quite large - for the larger chameleons a minimum of 3 feet by 3 feet by 4 feet tall should be provided - but the more space the better. Ample ventilation is required, and a cage screened on three sides is best, with poly mesh or vinyl coated wire preferred to prevent injury due to toes becoming caught. Lots of branches of various diameters need to be provided for climbing and the bulk of the cage space should be filled with branches or live foliage. Ensure that the plants are not toxic, as the chameleon may sample the foliage. Some enthusiasts recommend avoiding ficus plants as well. Substrate made up of small particles (gravel, sand, bark, moss) should be avoided to prevent the chameleon from accidentally eating it while catching prey. Several basking areas of various temperatures must also be provided, ranging from the upper limit of the species temperature preference to the loser end of the range, to allow the chameleons to thermoregulate.

